Escherichia coli
- Model organism
- Years of experience
- Largest synthetic biology toolbox available
Bacillus sp.
- Secretion of heterologous proteins
- Long history of industrial exploitation
Pseudomonas putida
- High tolerance to solvents
- Diverse metabolism
- Well-defined genetic toolbox
Streptomyces sp.
- Complex secondary metabolism
- Producer of numerous medical compounds
Corynebacterium glutamicum
- Heterologous protein and small molecule secretion
- High cell-specific productivity
Vibrio natriegens
- Fast-growing molecular biology host
- Doubling time <10 min
Saccharomyces cerevisiae
- GMP-compliant for pharma
- GRAS
- Large toolbox available
- Highly scalable
Pichia pastoris
- Production of secreted recombinant proteins
- Engineered for humanised glycosylation
Aspergillus niger
- Capacity to secrete large amounts of enzymes
- Production of citric acid
- Various metabolites
CHO cells
- Mammalian cell line
- Human post-translational modifications
- Targeted gene integration