Hosts

Ingenza’s diverse range of bacterial, yeast and mammalian production platforms offer tailored, scalable biomanufacturing for applications using biologics, enzymes or chemicals. The productivity, quality management and process robustness essential for commercial operations in our host platforms is underpinned by:

  • customised feedstock testing and development
  • statistical design of experiments-based media and growth optimisation
  • long-proven culture protocols
  • rigorous cell banking

Escherichia coli

  • Model organism
  • Years of experience
  • Largest synthetic biology toolbox available

Bacillus sp.

  • Secretion of heterologous proteins
  • Long history of industrial exploitation

Pseudomonas putida

  • High tolerance to solvents
  • Diverse metabolism
  • Well-defined genetic toolbox

Streptomyces sp.

  • Complex secondary metabolism
  • Producer of numerous medical compounds

Corynebacterium glutamicum

  • Heterologous protein and small molecule secretion
  • High cell-specific productivity

Vibrio natriegens

  • Fast-growing molecular biology host
  • Doubling time <10 min

Saccharomyces cerevisiae

  • GMP-compliant for pharma
  • GRAS
  • Large toolbox available
  • Highly scalable

Pichia pastoris

  • Production of secreted recombinant proteins
  • Engineered for humanised glycosylation

Aspergillus niger

  • Capacity to secrete large amounts of enzymes
  • Production of citric acid
  • Various metabolites

CHO cells

  • Mammalian cell line
  • Human post-translational modifications
  • Targeted gene integration

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