![](https://www.ingenza.com/wp-content/themes/ingenza2022/images/hosts/p.pastoris.jpg)
Host
- P. Pastoris HCD fermentation
- Tolerance to target via removable fluorescent tag
![](https://www.ingenza.com/wp-content/themes/ingenza2022/images_2022/case-studies/case-study-7/diagram1.png)
Build & Screen
- Design and integration of constructs
- FACS supported visABLE® screen for jackpot clones with optimal productivity/stability
![](https://www.ingenza.com/wp-content/themes/ingenza2022/images_2022/case-studies/case-study-7/image1.jpg)
Manufacture
- Manufacturing process developed - 20 L fermentation and scalable DSP
- Multi-gram >95% pure, fully active target per run
![](https://www.ingenza.com/wp-content/themes/ingenza2022/images_2022/case-studies/case-study-7/diagram2.jpg)
Pre-clinical testing
- Drug substance formulated at 3rd party
- Successful pre-clinical toxicology