Inside Ingenza – Complex Protein
In this instalment of our Inside Ingenza series, Fraser Brown – Ingenza’s Head of Chemistry and Analytical Development – talks about a particularly complex protein we worked with.
White paper: Brewing success: fermentation development at Ingenza
Fermentation plays a vital role in delivering high quality, scalable products for biopharmaceuticals and sustainable chemicals. But success depends on precisely controlling parameters such as temperature, pH, nutrient supply and oxygen levels. Optimising these conditions – and scaling them efficiently…
Deuterium: Slowing Metabolism One C–H Bond At A Time
Deuterium (D) is a heavy stable isotope of hydrogen (H) and is an increasingly utilised strategic modification to improve drug performance (Di Martino, 2023). The substitution of deuterium isotope for hydrogen offers improved pharmacokinetic performance by extending drug half-life against metabolism…
Nick Challoner appointed as Chief Executive Officer at Ingenza
Ingenza Limited, a technology driven contract research, development and manufacturing organisation (CRDMO), has announced the appointment of Nick Challoner as its new Chief Executive Officer, effective the 1st of October, 2025. Nick brings over 30 years of experience in business…
How platform technologies are shaping the pharmaceutical industry
The pharmaceutical landscape is evolving rapidly with the introduction of platform technologies, often enhanced by machine learning (ML), and Ingenza is one of the few contract, research, development and manufacturing organisations (CRDMOs) to embrace this approach. Ingenza’s inGenius® platform plays a pivotal role in accelerating…
Ingenza announces move to purpose-built facility at Edinburgh Technopole
Ingenza is delighted to announce its relocation to The Moubray Building at Edinburgh Technopole, part of the Pioneer Group. The new site is still within the Midlothian Science Zone – a world-leading centre of research excellence in life sciences –…
Webinar – Enzymatic Precision: Advancing Complex Small Molecule Synthesis using Biocatalysis
This webinar highlights the opportunity for the exquisite selectivity of enzymatic biotransformations, conducted in vitro or in vivo, to overcome these challenges of tomorrow’s small molecule pharmaceutical manufacturing.
Steering success with streamlined project management
Ingenza recently welcomed Lisa Fraser as the company’s first Senior Project Manager. Lisa brings extensive leadership and project management experience to her new role, and she will no doubt be instrumental in driving Ingenza’s strategic goals and supporting its pioneering work in…
White paper: The advantages of biocatalysis in pharmaceutical manufacturing
The use of enzymes as catalysts in chemical reactions offer several advantages for pharmaceutical manufacturing over traditional chemical production routes. Benefits include high selectivity, product purity and mild reaction conditions that reduces energy consumption and waste whilst removing the use…
Ingenza partners with HydRegen to advance sustainable biomanufacturing
Ingenza has partnered with Oxford-based biotech company HydRegen to develop a more sustainable and cost-effective method for manufacturing amine-based chemicals, eliminating the need for heavy metal catalysts. The company turned to Ingenza to help improve the expression levels of a new candidate biocatalyst,…