![](https://www.ingenza.com/wp-content/themes/ingenza2022/images/hosts/e.coli.jpg)
Host
- Recombinant E. coli used to express target protein therapeutic
![](https://www.ingenza.com/wp-content/themes/ingenza2022/images_2022/case-studies/case-study-4/graph1.jpg)
Build
- Design/construct codon-variant library
- Library fused to gene encoding visible reporter
![](https://www.ingenza.com/wp-content/themes/ingenza2022/images_2022/case-studies/case-study-4/diagram1.png)
Screen
- Solid-phase screen identified best expressed clones
- Liquid phase assay confirmed productivity of target
- Reporter removed, purity of target characterised